WSUS Fails to configure

Hi,

After having issues with WSUS - reinstalled to no avail but receiving the following when on post installation notifications 

Log file is located at C:\Users\a-pskinner\AppData\Local\Temp\tmp424D.tmp
Post install is starting
Fatal Error: Failed to start and configure the WSUS service

Receiving the below in the error log

CreateDefaultSubscription failed. Exception: System.Web.Services.Protocols.SoapException: System.Web.Services.Protocols.SoapException: Server was unable to process request. ---> System.TypeInitializationException: The type initializer for 'Microsoft.UpdateServices.Internal.ApiRemoting' threw an exception. ---> System.UnauthorizedAccessException: Access to the path 'Update Services' is denied.
   at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
   at System.IO.Directory.InternalCreateDirectory(String fullPath, String path, Object dirSecurityObj, Boolean checkHost)
   at System.IO.Directory.InternalCreateDirectoryHelper(String path, Boolean checkHost)
   at System.IO.Directory.CreateDirectory(String path)
   at Microsoft.UpdateServices.Log.GetUsableLogFileName(String fileName, LogFileLocation& actualLogLocation)
   at Microsoft.UpdateServices.Log.InitializeFromConfig()
   at Microsoft.UpdateServices.Log.InitializeIfNeeded()
   at Microsoft.UpdateServices.Internal.ApiRemoting..cctor()
   --- End of inner exception stack trace ---
   at Microsoft.UpdateServices.Internal.ApiRemoting..ctor()
   --- End of inner exception stack trace ---
   at Microsoft.UpdateServices.Internal.BaseApi.SoapExceptionProcessor.DeserializeAndThrow(SoapException soapException)
   at Microsoft.UpdateServices.Internal.DatabaseAccess.AdminDataAccessProxy.GetServerVersion()
   at Microsoft.UpdateServices.Internal.BaseApi.UpdateServer.CreateUpdateServer(String serverName, Boolean useSecureConnection, Int32 portNumber)
   at Microsoft.UpdateServices.Internal.BaseApi.UpdateServer..ctor(Boolean bypassApiRemoting)
   at Microsoft.UpdateServices.Setup.StartServer.StartServer.CreateDefaultSubscription()
2016-04-27 09:37:03  StartServer encountered errors. Exception=System.Web.Services.Protocols.SoapException: Server was unable to process request. ---> System.TypeInitializationException: The type initializer for 'Microsoft.UpdateServices.Internal.ApiRemoting' threw an exception. ---> System.UnauthorizedAccessException: Access to the path 'Update Services' is denied.
   at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)
   at System.IO.Directory.InternalCreateDirectory(String fullPath, String path, Object dirSecurityObj, Boolean checkHost)
   at System.IO.Directory.InternalCreateDirectoryHelper(String path, Boolean checkHost)
   at System.IO.Directory.CreateDirectory(String path)
   at Microsoft.UpdateServices.Log.GetUsableLogFileName(String fileName, LogFileLocation& actualLogLocation)
   at Microsoft.UpdateServices.Log.InitializeFromConfig()
   at Microsoft.UpdateServices.Log.InitializeIfNeeded()
   at Microsoft.UpdateServices.Internal.ApiRemoting..cctor()
   --- End of inner exception stack trace ---
   at Microsoft.UpdateServices.Internal.ApiRemoting..ctor()
   --- End of inner exception stack trace ---
2016-04-27 09:37:03  Microsoft.UpdateServices.Administration.CommandException: Failed to start and configure the WSUS service
   at Microsoft.UpdateServices.Administration.PostInstall.Run()
   at Microsoft.UpdateServices.Administration.PostInstall.Execute(String[] arguments)

Also receiving this in event log 

Event code: 3001 
Event message: The request has been aborted. 
Event time: 27/04/2016 09:31:53 
Event time (UTC): 27/04/2016 08:31:53 
Event ID: c841e1a31aac4894a0df1a219bad01f3 
Event sequence: 340 
Event occurrence: 142 
Event detail code: 0 
 
Application information: 
    Application domain: /LM/W3SVC/589721959/ROOT/ClientWebService-1-131062190290281279 
    Trust level: Full 
    Application Virtual Path: /ClientWebService 
    Application Path: C:\Program Files\Update Services\WebServices\ClientWebService\ 
    Machine name: GBHBMGT2 
 
Process information: 
    Process ID: 17724 
    Process name: w3wp.exe 
    Account name: NT AUTHORITY\NETWORK SERVICE 
 
Exception information: 
    Exception type: HttpException 
    Exception message: Request timed out.

 
 
Request information: 
    Request URL: http://gbhbmgt2:8530/ClientWebService/client.asmx 
    Request path: /ClientWebService/client.asmx 
    User host address: 172.40.1.210 
    User:  
    Is authenticated: False 
    Authentication Type:  
    Thread account name: NT AUTHORITY\NETWORK SERVICE 
 
Thread information: 
    Thread ID: 68 
    Thread account name: NT AUTHORITY\NETWORK SERVICE 
    Is impersonating: False 
    Stack trace: 
 
 
Custom event details: 

Any help would be appreciated

Thanks